Industrial Intermediates
Number of EDCs: 164
Chemical nameChemical identifierLiterature identifier
AcetaldehydeDED000002PMID:22538484, PMID:6723515, PMID:7128453
BenzeneDED000003DOI:10.3109/10915818909018060, PMID:33502539
PhloroglucinolDED000005PMID:14925120
EthanolDED000009PMID:21432428, PMID:21463340, PMID:2318350, PMID:37994192, PMID:611632
FormaldehydeDED000010PMID:12916763
IodineDED000013PMID:28205391
MethanolDED000014PMID:12490131, PMID:9241670
CaffeineDED000036PMID:23590819, PMID:3607108, PMID:36555195
PhloretinDED000074PMID:24487097
Tetramethylthiuram disulfideDED000083PMID:12606370, PMID:8318751, PMID:8725639
ChloroformDED000101PMID:15758249
DichloromethaneDED000108PMID:6701900, PMID:9804871
Ethylene oxideDED000110PMID:2815085
Trichloroacetic acidDED000113PMID:29294279, PMID:38266585
Acetyl tributyl citrateDED000114PMID:28235592, PMID:35567983
IsopreneDED000118PMID:7923161
Tetrabromobisphenol ADED000121PMID:15635150, PMID:18255212, PMID:18313098, PMID:20399831, PMID:25146423, PMID:25223798, PMID:26253174, PMID:26979758, PMID:28564613, PMID:28616630, PMID:32416200, PMID:33099281, PMID:35101577, PMID:35321852, PMID:36499108, PMID:37487893, PMID:38128231, PMID:38763426, PMID:38997027, PMID:39134236, PMID:39236844
3-Chloro-1,2-dihydroxypropaneDED000144PMID:6612740, PMID:7663078
ButylphenDED000146PMID:17904329, PMID:8593856
1,4-CyclohexanedimethanolDED000159PMID:26289545
EpichlorohydrinDED000162PMID:2258022, PMID:2767356, PMID:4833816, PMID:6612740
Vinyl acetateDED000165PMID:6845374
Ethylene glycol monomethyl etherDED000167PMID:1288759, PMID:4065311, PMID:6499822
HexaneDED000170PMID:26410608, PMID:2764718
Ethylene glycol monobutyl etherDED000173PMID:12571679
NonaneDED000174PMID:19152832, PMID:7423533
PropyleneDED000175PMID:12748682
NoramidopyrineDED000200PMID:29289696
MedroxyprogesteroneDED000201PMID:14751673, PMID:6458924
OctamethylcyclotetrasiloxaneDED000205PMID:11509742, PMID:17418525, PMID:34884750
DibutyldichlorotinDED000215PMID:2466803
t-Butyl methyl etherDED000233PMID:10746943, PMID:10966521, PMID:19344668, PMID:19595749, PMID:35131586
2,4,2',4'-TetranitrobiphenylDED000237PMID:28430429
1,2,5,6,9,10-HexabromocyclododecaneDED000252PMID:15585367
Sodium silicateDED000264PMID:4346985
ChromiumDED000268PMID:23470461, PMID:28911802
1,2,4-Trichlorodibenzo-1,4-dioxinDED000319PMID:1949037
Dibenzo(b,e)(1,4)dioxin, 2,3-dibromo-7,8-dichloro-DED000327DOI:10.1016/0045-6535(91)90040-K
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxideDED000333PMID:29144987, PMID:34050522, PMID:37167865, PMID:37802009
2-Hydroxybenzo(a)pyreneDED000336PMID:626971
2,2',4,4',5,5'-Hexachlorodiphenyl etherDED000347PMID:9177011
2,3,5,6-TetrachlorohydroquinoneDED000359PMID:1949037, PMID:2017761
2,2-Bis(4-hydroxyphenyl)-1,1,1-trichloroethaneDED000371PMID:22549810
4,4'-DiiodobiphenylDED000372PMID:15585367
2,3',4',6-Tetrachlorodiphenyl etherDED000382PMID:9177011
EquolDED000389PMID:18656497, PMID:23220561, PMID:24211351
2,2',4,5,6'-Pentachlorodiphenyl etherDED000397PMID:9177011
3,3',4,4',5,5'-HexabromobiphenylDED000400DOI:10.3109/10915818209018016, PMID:17447562
4-Hydroxy-2',4',6'-trichlorobiphenylDED000401PMID:8318755
1,1'-Biphenyl, 2,2',4',5,5'-pentachloro-3-(methylsulfonyl)-DED000404PMID:10330683, PMID:10739067, PMID:18025052
2,3',4,4'5,5'-HexabromobiphenylDED000407DOI:10.3109/10915818209018016
1,1'-Biphenyl, 2,2',3,4,5'-pentachloro-3'-(methylsulfonyl)-DED000408PMID:10739067
1,1'-Biphenyl, 2,2',4,5,5'-pentachloro-4'-(methylsulfonyl)-DED000409PMID:10330683, PMID:10739067, PMID:18025052
1,1'-Biphenyl, 2,2',3,4,5'-pentachloro-4'-(methylsulfonyl)-DED000410PMID:10330683, PMID:10739067
Dibenzo(b,e)(1,4)dioxin, 2-bromo-3,7,8-trichloro-DED000413DOI:10.1016/0045-6535(91)90040-K
1,1'-Biphenyl, 2,2',3,4,5,5'-hexachloro-3'-(methylsulfonyl)-DED000415PMID:10739067, PMID:9765071
1-Chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzeneDED000419PMID:11869873, PMID:1591480, PMID:19900470, PMID:2055367, PMID:7579910
1,1'-Biphenyl, 2,2',3,4',5',6-hexachloro-4-(methylsulfonyl)-DED000420PMID:10739067, PMID:16216300, PMID:9765071
1,1'-Biphenyl, 2,2',3,3',4',6-hexachloro-5-(methylsulfonyl)-DED000421PMID:10739067, PMID:9765071
1,1'-Biphenyl, 2,2',4',5-tetrachloro-3-(methylsulfonyl)-DED000422PMID:10330683, PMID:10739067
3-Methylsulfonyl-2,3',4',5-tetrachlorobiphenylDED000426PMID:10330683, PMID:10739067
1,1'-Biphenyl, 2,2',3,4',5',6-hexachloro-5-(methylsulfonyl)-DED000427PMID:10739067, PMID:16216300, PMID:9765071
Oxanthrene, 2,3,7-tribromo-8-chloro-DED000432DOI:10.1016/0045-6535(91)90040-K
Beta-SitosterolDED000435PMID:10825674, PMID:15597897
2-ButenalDED000449PMID:16442836
HydroxytamoxifenDED000450PMID:15315699
CinnamaldehydeDED000454PMID:2606408, PMID:7813982
3,3-dibromobisphenol ADED000456PMID:11693576
3-monobromobisphenol ADED000457PMID:11693576
2,2-bis(4-hydroxyphenyl)-propanolDED000458PMID:9449681
3,3-bis(4-hydroxyphenyl)pentaneDED000462PMID:9449681
3,5-Dibromo-2-(2,4-dibromophenoxy)phenolDED000477PMID:16177243, PMID:18022659, PMID:20549613
4,4'-Propane-1,1-diyldiphenolDED000480PMID:9449681
Biochanin ADED000483PMID:12153753, PMID:36555195
LuteolinDED000485PMID:23836117
3-MethylquercetinDED000488PMID:14706564
MyricetinDED000489PMID:24487097
9,10-dihydroxy-12-octadecenoic acidDED000492PMID:16330350
Amsonic acidDED000494PMID:1316972
LeadDED000504PMID:12220594, PMID:1909817, PMID:22806249, PMID:25434758, PMID:35104782, PMID:37659646, PMID:7444965, PMID:8199261, PMID:8619245, PMID:8989890
1,2-Diphenylcyclobutane, trans-DED000532PMID:11485868
2-OH-BDE-123DED000534PMID:18313098
2,3',4',6-Tetrabromodiphenyl etherDED000539PMID:11861977, PMID:14999130, PMID:18313098, PMID:18470304, PMID:22127959, PMID:25060363, PMID:28644858, PMID:8134923
Sodium nitriteDED000547PMID:2807101, PMID:3352650, PMID:9207897
Ascorbic acidDED000555PMID:23590819
MonophenyltinDED000566PMID:25465476
Benzo(a)pyreneDED000576PMID:18634860, PMID:21737371, PMID:22960446, PMID:23037998, PMID:23059060, PMID:23280776, PMID:24769007, PMID:27221463, PMID:28043741, PMID:28263535, PMID:29649501, PMID:30443902, PMID:31085209, PMID:32023792, PMID:32670863, PMID:33254415, PMID:33297042, PMID:33433340, PMID:33513405, PMID:34050522, PMID:34459573, PMID:35912572, PMID:36460192, PMID:37167865, PMID:37369342, PMID:37783996, PMID:37802009, PMID:38583661, PMID:38701656, PMID:38763096, PMID:39108652, PMID:39226951, PMID:39454710
Dibutyl phthalateDED000581PMID:10641015, PMID:15518916, PMID:15620428, PMID:15883486, PMID:16493179, PMID:17379376, PMID:17654256, PMID:17725530, PMID:19533667, PMID:19903717, PMID:21657945, PMID:21841806, PMID:22179484, PMID:22238399, PMID:23314658, PMID:23536518, PMID:23766129, PMID:25016925, PMID:25614580, PMID:25697569, PMID:25765776, PMID:26948521, PMID:27943041, PMID:28104404, PMID:28641505, PMID:28823096, PMID:28898977, PMID:28918339, PMID:29064414, PMID:29137315, PMID:29969652, PMID:30031264, PMID:30391722, PMID:30940548, PMID:31158667, PMID:31318015, PMID:31387634, PMID:31979393, PMID:32292708, PMID:32334352, PMID:32388187, PMID:32497820, PMID:32810643, PMID:33004990, PMID:33086118, PMID:33920546, PMID:33983380, PMID:34015706, PMID:34088158, PMID:34097988, PMID:34280466, PMID:34395617, PMID:34474386, PMID:34488563, PMID:34793900, PMID:34864161, PMID:35567983, PMID:35605887, PMID:35919841, PMID:35955852, PMID:36215882, PMID:36230992, PMID:36308879, PMID:37167869, PMID:37237912, PMID:37277016, PMID:37762641, PMID:37977363, PMID:38246300, PMID:39262327, PMID:39560046
TrichloroethyleneDED000595PMID:10773841, PMID:12759095, PMID:29294279
TributylchlorostannaneDED000623PMID:12083789, PMID:12773765, PMID:14667468, PMID:16513093, PMID:16613991, PMID:18246498, PMID:20052771, PMID:22362710, PMID:22972585, PMID:23523586, PMID:23913619, PMID:2466803, PMID:24895210, PMID:25101840, PMID:25819109, PMID:25898838, PMID:27267847, PMID:27521499, PMID:28161095, PMID:28781899, PMID:30831249, PMID:31821856, PMID:31927052, PMID:32783468, PMID:36858099, PMID:37406193, PMID:38621455, PMID:7900160
Nickel sulfateDED000630PMID:31392545, PMID:9494062
Ammonium chlorideDED000635PMID:10550527, PMID:31572187
TetrachloroethyleneDED000636PMID:12759095, PMID:17066414, PMID:31310931, PMID:7251397, PMID:8427017
Perfluoro-1-iodohexaneDED000646PMID:21990342, PMID:29665550
Phenol, 4,4'-(1,1-dimethyl-3-methylene-1,3-propanediyl)bis-DED000653PMID:20435109, PMID:30552153
4-hydroxy-2,3,3,4,5-pentachlorobiphenylDED000659PMID:15310862, PMID:18025052, PMID:29788408
4,4'-CyclohexylidenebisphenolDED000662PMID:17904329, PMID:31388671, PMID:32387340, PMID:33753083, PMID:37939739
Diisononyl phthalateDED000667PMID:11099647, PMID:14580783, PMID:15013064, PMID:16493179, PMID:17654256, PMID:20077217, PMID:21075200, PMID:21633115, PMID:22813627, PMID:28300662, PMID:28893586, PMID:30649530, PMID:31904422, PMID:32165126, PMID:33223173, PMID:33391822, PMID:33983380, PMID:36929940, PMID:37482143, PMID:38926453
ApigeninDED000671PMID:22414680, PMID:24487097, PMID:30678243
4-hydroxy-2,2,3,4-tetrabromodiphenyl etherDED000684PMID:28299817, PMID:29357290
Vinyl chlorideDED000695PMID:4092642
1,2-Propylene oxideDED000696PMID:12748685, PMID:17179639, PMID:6648426
Toluene-2,4-diamineDED000700PMID:3199457, PMID:3937900, PMID:4093994
1,2,3-TrichloropropaneDED000701PMID:12692652, PMID:3184199
4-NitroanilineDED000702PMID:2258023
Bis(4-aminophenyl) etherDED000704PMID:3881621, PMID:716159
N-MethyldiethanolamineDED000705PMID:31310931
4-XyleneDED000706PMID:7233451
4-ChloroanilineDED000707PMID:12704433
1,3-ButadieneDED000708PMID:2401271, PMID:3591659
AcrylonitrileDED000709PMID:12044704, PMID:18293209, PMID:3388448, PMID:6777907
FuranDED000710PMID:31108444, PMID:31121209, PMID:32174189
DiolamineDED000711PMID:31310931
Methylenedianiline dihydrochlorideDED000730PMID:12750745, PMID:3712494, PMID:4293143
Sodium sulfideDED000764PMID:31572187
Zinc dibutyldithiocarbamateDED000772PMID:689578
Dibutyltin dilaurateDED000777PMID:2899427
CatecholDED000794PMID:36241036, PMID:39512757
Chloroacetic AcidDED000795PMID:36963690
O-CresolDED000796PMID:39512757
Methyl SalicylateDED000817PMID:39454092
4-ChlorophenolDED000820PMID:36241036
1,1',1''-(Chlorosilylidyne)tris(benzene)DED000832PMID:31927052
2-BromophenolDED000845PMID:36241036
2,4-Di-tert-butylphenolDED000846PMID:36750942
1,2-DibromoethaneDED000847PMID:9804871
Ethyl SalicylateDED000852PMID:39454092
ChloranilDED000853PMID:38555059
Diallyl phthalateDED000855PMID:33983380
CyanamideDED000859PMID:33892370
DecamethylcyclopentasiloxaneDED000860PMID:37112528, PMID:37551828
4-HexylphenolDED000875PMID:38997027
Aluminum ChlorideDED000883PMID:32485499, PMID:34726835, PMID:34958889, PMID:36695414
Sodium NitrateDED000885PMID:34409734
Nickel DichlorideDED000886PMID:32901497
3,5-DichlorocatecholDED000889PMID:39512757
4-AminoacetanilideDED000893PMID:34014586
3-FluorocatecholDED000909PMID:39512757
3,3,4,4,5,5,6,6,7,7,8,8,8-Tridecafluorooctan-1-olDED000914PMID:38535903
Phenol, 4,4'-(1-methylethylidene)bis(2-(2-propen-1-yl)-DED000918PMID:38128231
1,1,1-Tris(4-hydroxyphenyl)ethaneDED000934PMID:32004960
Benzene, 2,4-dimethoxy-1-methyl-DED000935PMID:39512757
4-AminocatecholDED000942PMID:39512757
4-Fluoro-1,2-benzenediolDED000945PMID:39512757
CatecholamineDED000950PMID:39512757
Bis(4-hydroxyphenyl)diphenylmethaneDED000953PMID:32508751, PMID:37816402
3-BromocarbazoleDED000955PMID:32344252, PMID:36522090
1,3,6,8-TetrabromocarbazoleDED000956PMID:32344252
4,4'-(9-Fluorenylidene)dianilineDED000966PMID:36270036
N-(2,3-dimethylphenyl)-2-morpholin-4-ylacetamideDED000968PMID:38040386, PMID:38360075
9-(nonafluorobutyl)-2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-oneDED000973PMID:35093747
9,9-Bis[4-(2-hydroxyethoxy)phenyl]fluoreneDED000984PMID:35878500
1H,1H,8H,8H-Perfluorooctane-1,8-diolDED000986PMID:38535903
4,4'-(3,3,5-Trimethylcyclohexylidene)bis(phenol)DED000988PMID:39520287
2,7-DibromocarbazoleDED001005PMID:32344252, PMID:36522090
CyantraniliproleDED001008PMID:34968715
2-Bromo-9H-carbazoleDED001014PMID:32344252, PMID:36522090
5-(1,2,2,2-Tetrafluoro)ethoxy-perfluoro-3-oxa-4-methylpentanesulfonic acidDED001016PMID:38535903
1,2,9,10-TetrachlorodecaneDED001018PMID:38331103
2-(3-Chloro-4-hydroxyphenyl)-2-(4-hydroxyphenyl)propaneDED001021PMID:38128231
1,2-DichlorotetradecaneDED001023PMID:38331103
Chloro(iodo)acetic acidDED001025PMID:36963690
Bisphenol A monosulfateDED001031PMID:35041905
2-[(Dimethoxyphosphoryl)sulfanyl]butanedioic acidDED001033PMID:32007685
DISCLAIMER

We have built a comprehensive resource which compiles potential endocrine disrupting chemicals (EDCs) based on the observed adverse effects or endocrine-mediated endpoints in published experiments on humans or rodents to support basic research. We are not responsible for any errors or omissions in the published research articles or supporting literature on potential EDCs compiled in this resource. Users are advised to exercise their own judgement on the weight of evidence for potential EDCs compiled in this resource. Importantly, our sole goal to build this resource on potential EDCs is to enable future basic research towards better understanding of the systems-level perturbations upon chemical exposure rather than influencing regulatory advice on chemical use.